https://mindlab-blog-drafts.pages.dev/tags/threat-overvaluation/Recent content in Threat Overvaluation on MindLAB Neuroscience — Draft ReviewHugo -- 0.156.0en-us2026 Dr. Sydney Ceruto — MindLAB NeuroscienceTue, 05 May 2026 00:00:00 +0000https://mindlab-blog-drafts.pages.dev/posts/orbitofrontal-cortex-ocd/Tue, 05 May 2026 00:00:00 +0000https://mindlab-blog-drafts.pages.dev/posts/orbitofrontal-cortex-ocd/<h1 id="orbitofrontal-cortex-overvaluation--why-your-brain-treats-normal-thoughts-as-catastrophic">Orbitofrontal Cortex Overvaluation — Why Your Brain Treats Normal Thoughts as Catastrophic</h1> <p><img alt="A single orbitofrontal cortex rendered in luminous copper at the moment of a hyperactive threat-valuation signal — Dr. Sydney Ceruto, MindLAB Neuroscience." loading="lazy" src="https://mindlab-blog-drafts.pages.dev/images/posts/orbitofrontal-cortex-ocd-hero.webp"></p> <p>The orbitofrontal cortex is the structure that assigns emotional and threat value to incoming information — and in OCD, it does so with miscalibrated catastrophic weight. Hyperactive lateral OFC signaling exaggerates the predicted aversiveness of ordinary thoughts, then drives the ventral striatum into the loop that becomes a compulsion. The intrusive thought is not the problem. The threshold is.</p>