Epigenetic Inheritance of Family Trauma | MindLAB

Epigenetic Inheritance of Family Trauma: How Your Parents’ Stress Lives in Your DNA Epigenetic inheritance of family trauma is the biological mechanism by which a parent’s or grandparent’s stress exposure alters which of their children’s genes get expressed — without changing the underlying DNA sequence. Methylation marks on NR3C1 and FKBP5 carry an HPA-axis signature across generations, and recent human cohorts have now detected that signature three generations out, long before the affected child is conscious of any family history. ...

April 23, 2026 · 17 min · 3545 words · Dr. Sydney Ceruto